Chances are if you've been in your local Walmart or tackle store looking to purchase a spool of line you've seen to many brands/types of line to count.  It's a bit overwhelming.  Our goal with this article is to make it very simple and easy for the most inexperienced angler to understand then properly chose the type of line that best suits the situation.  This is not scripture, just my opinions based on my experience as a full time guide.  I'll keep this short and to the point. 

Monofilament: 

Monofilament has been around forever.  For the longest it was the "go to" for everything, and still to this day is a good all around line.  It's easily the most affordable of the big 3 and can be found in small or large spools in most every tackle store in the country. 
ADVANTAGES:  Again, it's cheap.  Comes in numerous colors, neon green, camo green, clear, blue, fluorescent blue, red, etc, etc.  So if you like to be able to see your line, Mono is a good option.  It's also great for night fishing.  The fluorescent blue glows under black lights which makes night fishing much more convenient giving you the ability to see your line when tying knots, netting fish, and of course fishing.  I've grew up using fluorescent blue line at night and still do to this day.  Also Mono floats so it's a great choice when fishing topwater or any bait you're trying to keep at or near the surface. 
DISADVANTAGES:  Lighter tests such as 4 and 6lb test tangle really easy and doesn't cast or handle near as good.  Mono isn't near as abrasion resistant as Braid or Fluro.  Mono floats and will stretch making it hard to get baits like crankbaits to reach their maximum depth.  With a good rod you can actually feel 10lb Mono stretching when using a big crankbait.  Best use:  In my opinion Mono is best used when fishing at night and when used with topwater or lures you are trying to keep near the surface (burning spinnerbaits, weighless worms).  When not to use Mono:  I never use Mono when fishing bottom baits such as worms, jigs, or when using hard baits I'm trying to get to maximum depths such as Jerkbaits, Crankbaits, or deep Spinnerbaits.